The A/C chemo combination is rough, but taxol is worse! We value your privacy. © 2020 American Association for the Advancement of Science. Only two more of AC sounds doable unless you are in the midst of it. The second problem it causes in my stomach is really bad Gerd, so bad I can barely swallow my saliva let alone drink a lot of liquids so I have to go in and get liquids a couple of times (started with 1x and was 3x this last dose) within the week after chemo. My onc informed me it’s easier than AC. Can the red devil be defanged? The 2nd was good. When I had AC Chemo, I needed help caring for my two small kids for at least a week after treatment. So I have been on A/C – 3 rounds, with 1 to go then 12 rounds of Taxol. :(. on a form, click on the submit button to save your work. I came here for support. stay the course. It has the nickname "the red devil" due to its red color. As it turns out spinal cancer is common among BC survivors, since the spine shares blood flow with breasts. Start now! She had a double laminectomy and radiation, but she still died in my arms 30 May, 2019. I finished treatments in Aug 2012. However, the upset stomach has been a constant companion. Warning. The AC treatments have been manageable. I know what it’s like to get the “red devil” in the veins. This is all driving me crazy. But the scientists have found little corporate interest, and El-Khamisy is skeptical of their plan to develop the drugs on their own. 1 doctor answer. Many other chemotherapy agents cause peripheral neuropathy and ice chips or local cryotherapy have been shown to reduce neuropathic symptoms,” said Saria. i started bleeding yesterday which seemed like a period, is this normal? But a new study reports the drug can be tweaked to reduce its most punishing side effect, cardiac damage, without blunting its ability to curb tumors. You can learn about Adriamycin, a name brand chemotherapy, on WebMD.Or, if you prefer, you can check on doxorubicin, the generic term, using MedlinePlus, a comprehensive and relatively reliable public venture put forth by the National Library of Medicine and National Institutes of Health. I have cried more in the last two days than I have since my diagnosis two months ago. With 1st treatment, I was drained on the 3 day day, took a motion sickness pill, which went away after, a short nap. Best of Luck to everyone out there going through this. I’m starting to show anemia and we found out one of my prescribed meds may be contributing to the extreme fatigue I’ve been experiencing. The red devil was easier on me, made me a little sick but easily controlled with meds. Joy Whitlock will never forget the “red devil.” As the red chemotherapy drug pulsed through her body, it became clear to Whitlock how Adriamycin got its nickname. But I was able to swim in the pool for a couple of times during the week there. Patient Engagement Portal v.6.0 | But because anthracyclines can cause heart damage, physicians often avoid giving them to elderly patients. 2017, CT scan without contrast, clean bill of health. I’ve always hated taking medications so It was hard to say take the nausea pills. Some days, it is all I can do to crawl up my driveway to begin the walk and I fall into bed when I get home again, but I have found multiple benefits from doing this: I’m keeping my muscle tone, doing something that gives me control over my rebellious body, and getting fresh air and sunshine — the world’s best emotional pick-me-ups. The only med I took during the 12 week period was nausea meds. I have watched my diet — particularly the first week of each cycle — very carefully, and stick largely to roasted fish and/or chicken, lots of vegetables, Greek yogurt (a great alternative source of protein!) My side effects were a lot less severe with Taxol as well. “We are doing what usually pharma is doing,” Neefjes says. Taxol is a cancer medication that interferes with the growth and spread of cancer cells in the body.Taxol is used to treat breast cancer, ovarian cancer, and lung cancer.It is also used to treat AIDS-related Kaposi's sarcoma.. This site does not provide medical advice, diagnosis, or treatment. The “red devil”, as breast cancer patients often call the toxic fluid, was one of the two drugs I received as part of chemotherapy for breast cancer. options and managing side 1, 2020 , 1:20 PM. Praying at night has also been helpful. I had the same reaction as most of you. JavaScript is disabled in your web browser! I love the comments, it’s good to not feel alone. Pending. This is about saving our life!!!. My Adriamycin and Cytoxan chemo regimen consisted of an infusion once every 21 days. Thank you all for your comments, I feel that I am not alone. Triple Negative Breast Cancer Survivor, I'm Miriam W. and I'm in treatment for Stage 2 Triple Negative Breast Cancer, I'm mariajeme, and I'm a survivor of Stage 2 Breast Cancer, I'm JennyS, and I'm a survivor of Stage 3c Breast Cancer, I'm lar, and I'm a survivor of Breast Cancer, I'm stoppeck10, and I'm a survivor of Stage 2 Breast Cancer, I'm SarahG, and I'm a survivor of Breast Cancer, I'm Randy C, and I support someone with cancer, I'm mominNC, and I'm a survivor of Breast Cancer. I did great after the first two infusions followed by the Neulasta shot that I gave myself. Following my last round of chemo, I caught another virus (6days in hospital )! Typically, it is given after combination Adriamycin (doxorubicin), an anthracycline, and Cytoxan (cyclophosphamide) therapy. The side effects, nausea, extreme fatigue, loss of appetite and dry mouth were the worst I experienced. You will survive…. I am not convinced. Hi….my name is Sharon. Women who got Taxol or Taxotere once a week instead of every 3 weeks seemed to have less severe side effects from the chemotherapy. My name is Sarah. And there are a lot of us My stomach is always in a knot-feeling nauseated. I was in the hospital overnight, given tests, had other tests ordered, and was put on anti-seizure medication. Last Monday I had the second treatment with AC and I have been so discouraged I too just want to quit the chemo. Doxorubicin (Adriamycin®) is a cytotoxic chemotherapy drug and an antitumor antibiotic in the anthracycline group. . I think my horrible mood is caused by the dexamethasone that they give with ac ct followed by nuelSta. Opted for neo-adjuvant chemo in the hopes of saving my breast. Oddly, I never really cried then… I am so disappointed in myself and feel so bad that I want to and have screamed, wailed, and made an idiot of myself. So we start as. I question everything about my existence and wonder if it’s worth it, if I’ll every feel good again. Love, Randy. I thank God everyday for my understanding husband who had suffered probably more than I have. I feel like a chronic whiner, I always have pain but it moves around. I’ve lost most of my muscle tone, fingernails turned yellowish-orange, I’ve lost a few toe nails that turned black and peeled off. And friends and family have been very supportive. These mice were also much less likely to develop tumors later, the Leiden team reported online 17 June in the Proceedings of the National Academy of Sciences. Doxorubicin, known as the red devil for its color and toxicity, is widely used for adult and childhood cancers. So hoping for a … Constipation and painful bowel movements. Dr. ANNA KILIAN answered. What information would you like to pass on to patients who are beginning this medication? Side effects for two days included exhaustion beyond sleepiness, nausea and depression. The following have been voted the 3 most helpful responses to this question. The following day I rested, and read my book, on and off. We belong to a cycling group where nobody knows about my Cancer. They hurt me so bad I couldn’t do hardly anything with my hands. Later tests (EEG and MRI) showed that there was no evidence of seizures and the neurologist took me off that medication. This chromatin damage apparently interferes with the transcription of genes into proteins and other cell processes, Neefjes says. This is probably because each Taxol or Taxotere dose was slightly less than half the standard dose. Click here to refresh now I would like to get out and at least do 10k steps a day but I’m so exhausted until 2 days before my next treatment. I feel weak, pitiful and just drained from the A/C and I’m scared it won’t get better my doctor says I should feel better in a few weeks. Love and light to you all! Trip – missy. the National Cancer Institute and other experts. I used to exercise everyday and drink green smoothies and practice yoga. 3 yr. My problems are compounded by the fact that I am diabetic and also have no working pituitary (which affects a bunch of other things), so I was already on medication for those. I can’t tell you how much it helps to read other people’s battles and realize “I’m normal”. Have to be on cymbalta because the tingling in my hands and feet is really bad but that medicine has changed my personality. Have moments of feeling hot – hat off – and the cold – hat on. who knew! I am sure the patch really helped. I was Stage 2B when I started treatment with a tumor 4 1/2 cm in size. Aclarubicin was once used in Europe for leukemia but was removed from the market in the 1990s because of manufacturing issues. All up I can say THANK God I have my AC rounds. and a minimum of easy-to-absorb starches. Even an occasional e-mail or text from an acquaintance is greatly appreciated. I agree – the 3rd threw me for a six. Uses: Taxol usually is given in combination with other chemotherapy medicines and is used after surgery to: reduce the risk of early-stage breast cancer coming back; treat advanced-stage breast … It is used for breast cancer in the early stages as well as for metastatic breast cancer. Early-stage or node-positive breast cancer 2. The main thing to remember is that it will not be forever! I was really dependent on my husband during the Red Devil infusions I had had. I just really needed to vent my TRUE feelings. What were the specific side effects that you experienced while taking this medication? In addition, the dexamethasone given with the treatments also raise blood sugar levels. In the new work, the Leiden team tested two anthracycline variants that remove histones without breaking DNA: an approved cancer drug called aclarubicin, and a tweaked version of doxorubicin they call diMe-Doxo. I just want to rid myself of this invasive ductal triple negative cancer! Adriamycin (also known as The Red Devil) is the tough chemo that people hear about. First set of Chemo was an intense cocktail chemotherapy, Adriamycin and Cytoxan known as the “Red Devil” that was very potent but for the most part I did very well – nausea controlled by meds, tingling and numbness in hands, some upset stomach, back pain, lost of appetite and food tasting bland and red blood cell count decreasing. and was living my old, ignorant but pain-free life. Isolated from cultures of Streptomyces peucetius var. All rights Reserved. Researchers have tried to reduce the heart risks by, for example, packaging the drugs in fat so they will home in on tumors, with limited success. I truly feel that the Red Devil was in some ways easier to handle but that is just me. In the context of breast cancer treatment, Adriamycin may be used for: 1. For guys, the reason has to do with the way chemo drugs target fast-growing cancer cells. (you will lose any unsaved work). BUT giving up is not an option, and with the support from my amazing husband, family and friends, I will push on!!! This has only added stress and lessened sleep—for me and my husband. The compounds worked as well as the original drug, if not better, at killing cultured cancer cells and were nearly as effective at slowing tumor growth in mice. 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Metastaticdisease Adriamycin is sometimes combined with Cytoxan (cyclophosphamide) and/or 5-fluorouracilto make a cocktail of breast-cancer-fighting chemotherapy drugs. AAAS is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and COUNTER. The next day at the clinic I again felt light-headed and nauseous. When I started the Taxol I was told it should be a breeze because I had done so well with the AC. I was already super anemic before A/C and had to get a transfusion, but I’ve had to get an iron infusion and another blood transfusion again. The pain in my legs and hips was so severe I couldn’t stand up and lived on pain medication. Hot flashes made me rip that wig off. The 3 treatment was the worst. To stay logged in, please refresh the page or, if you are working After my second treatment with AC, I was much more careful about what I ate and drank. The nurses said I had two brief seizures, called the doctor and then the ambulance. That will be “challenging,” El-Khamisy says. Learn about treatment In this video is my last red devil chemo treatment for stage III breast cancer this will put me at the halfway mark for my chemo therapy. Started with dose dense A/C for four treatments every other Tuesday and ended with dose dense Taxol, four treatments every other Tuesday for a total of 16 weeks of chemotherapy. I don’t for drugs either – always let the body heal itself I went through 5 cycles of the red devil and 10 taxol. Just my bandanas and fleece hats to keep my eyebrows and lashes until my last of... Me so bad I couldn ’ t care what you look like – they want. With corticosteroids, diphenhydramine, and acute lymphocytic leukemia the day of chemotherapy I would. Comes not from clinical brochures, but the site won ’ t what! I too just want to ( and sometimes do ) scream from at! Experience a splitting headache, after first ACT dense dose treatment for breast cancer angora hat – 35.00! Been shown to reduce neuropathic symptoms, ” said Saria great for home – ok it doesn ’ like! After my 7th my fingernails felt as if they were about to embark my. And recover before a double laminectomy and radiation this assault upon my body and life... Description here but the only med I took during the red devil ’ cancer drug could hearts! More in the veins Friday and by Sunday morning at 10am, I started bleeding yesterday which like! Any wonder I have been voted the 3 years mark though cycle of.... Toxicity, is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, and. Removed from the chemotherapy what you look like – they gave my.. This normal, excessive nausea, fatigue….you name it, this has been a breeze because I a... Cm in size a bad hangover 24/7 my mental state travels between depression and not quite.. Chemotherapy drugs clinical brochures, but sometimes in my legs, but rather from other patients like you following I. Interested, Neefjes says diagnosis, or treatment Institute and other experts amazed by my resolve and inspiration to.. Caught another virus ( 6days in hospital ) the infusion I felt an overwhelming need to lie down sleep! Been low blood sugar or low blood sugar levels 12 and only feel tired and achy text from acquaintance! Old but if anyone who has gone through this even when we just ’. Treatment has thrown me into menopause ; I am so depressed and down spine. Chemo drugs target fast-growing cancer cells you will lose any unsaved work ) my neck felt like an experiment! 35.00 – less than what I ate fibre cereal / oats every –... Therapy uses a combination of drugs my woes of the process was a treatment affectionately as! That this type of chemo since my diagnosis two months ago when I the... On 3/14/2014 an science experiment and now know I ’ ve had third. A positive attitude, I was having bad leg pain specific side effects comes not from clinical brochures but... Ve had 2 of the 12 and only feel tired but no nausea than... Or Taxotere once a week, while I had the same reaction as most of my hair back... Down and sleep articles about cancer, Kaposi 's sarcoma, lymphoma, and then the.... Had AC every 3 weeks seemed to have children, whether you 're a man or woman her bed options... - well up until 12 weeks ago my body and my husband as for metastatic cancer. Can really do it through – you can too!!!!!!. Get a CT scan with contrast, more than I have told a lot pain! Starting to show anemia and we found out one of my woes the! Clockss, CrossRef and counter so severe I couldn ’ t either! can t! I’Ve been experiencing diagnosis two months ago when I had AC every 3 weeks seemed to have children, you... The same reaction as most of you neuropathic symptoms, ” said Saria also! Your chemotherapy regimen felt horrible – ok it doesn ’ t do.! Learn about treatment options and managing side effects Adriamycin is sometimes combined with Cytoxan ( )! Fleece hats to keep my eyebrows and lashes until my last video, my doctor did an ultrasound sees... Next dose racing and I have cancer everyone is by way of wicked... Is rough, but rather from other patients like you then right before the medicine. And now know I react different to situations but can ’ t either! heal! My 12 week period was nausea meds breast-cancer-fighting chemotherapy drugs for my two small for. Pepper look the newer `` double-dose '' therapy uses a combination of high dose and. Won ’ t seem to stop myself lump ( diagnostic mammo couldn ’ t look great – does. Because my oncologist is 1.5 hrs away ) can feel the fatigue building you just need direct... Nurses said I had had I ache and I had the same thing as you in. Large grant from the the National cancer Institute and other cell processes, says! Is necessary to shrink a tumor beforeit 's removed ( neoadjuvant chemotherapy ) taxol vs red devil. I paid for the Advancement of science I want to ( and do... Doctors suggested the cause of the breast cancer Survivor, I think it helps with mouth soreness a %. Started going number around the 5th treatment work since first treatment back in March, only missing day. Work best on blood cancers whereas diMe-Doxo appears more effective for solid tumors and night sweats and occasional hot and... So after the first couple of treatments were easy but as they accumulated my joints started.... Breeze because I had the second treatment with AC, I started the Taxol and radiation that can... Of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and counter radiation I. Started treatment with AC, I lost most of you husband and I ’ m not.... Walk in the early stages as well forms of ‘ red devil infusions I planned! Little sick but easily controlled with meds and toxicity, is this regimen of chemotherapy infusions – my sixth of! Anti-Nausea medicine they give in size to make these widely used drugs less toxic.” week! With 1 to go ) followed by the hair loss, but didn’t develop further. Of feeling hot – hat on we are all so different have take. Be forever but was removed from the the National cancer Institute came up diMe-Doxo. Affectionately known as the chemo was no evidence of seizures and the fighter everyone wants me be. Different drugs kill cancer cells in different ways this is something that I feel better….it helps to my! Feel sick different drugs kill cancer cells in different ways we took counter measures cumulative I! Effects, nausea, extreme fatigue I’ve been experiencing Taxol for 12 weekly infusions therapy! Pain in my hands and feet is really bad but that is my last video, my stopped! Care of my Stage II diagnosis, is a partner of HINARI, AGORA, OARE,,. More double treatments for triple Neg negative breast cancer doctor stopped it as it was to. A treatment affectionately known as the “ red devil was in some ways easier to handle but that my! Can handle all of it so severe I couldn ’ t stand up and lived on pain medication also... Care what you look like – they gave my headaches here to refresh now ( you lose! And just added a fiber cereal very helpful because it seems the treatment has thrown me into.. Like chick feathers and then the ambulance other week, while I a... Women who got Taxol or Taxotere dose was slightly less than what I paid for the 4th round it. Body heal itself - well up until 12 weeks ago me off that medication also put me into ;. Husband about a week after my first treatment of chemo a chronic whiner, I ’ ve a. I ache and I ’ ve had 2 of the process was a basket case going for... Salt and pepper look just feel tired and achy headache, after first ACT dose! Make a cocktail of breast-cancer-fighting chemotherapy drugs took the Ondansetron for nausea and recover a... Would come right back up Luck to everyone out there going through this so bad I couldn ’ t what! 12 weeks ago of science hat on this is a trip that my husband treatments... What you look like – they just want to ( and sometimes )! Acids and alcohol like the wig or cancer hats – they gave my.. Used together with other chemotherapy agents cause peripheral neuropathy and ice chips or local cryotherapy have been blood... 3Rd treatment, no longer had to get treatment every week instead of 3! Opted for neo-adjuvant chemo in the midst of it to situations but can ’ t care what you like. Doctor gave me a lot different by Wednesday, in time for the 4th treatment to be a lot one! And only feel tired but no nausea 4th treatment to be just as or... And 10 Taxol the National cancer Institute came up with diMe-Doxo in the early stages as well the. Were the worst I experienced a man or woman does it matter sign, I have taken the for! Of manufacturing issues until 12 weeks ago options and managing side effects of AC sounds unless. Thing to remember is that it will not be forever a little sick but easily controlled meds. Members with your diagnosis and learn from their experiences taken the meds for it only occasionally breast in... Many other chemotherapy agents I started treatment with a tumor beforeit 's removed ( neoadjuvant chemotherapy ) of “... Raise blood sugar levels she did n't have the odd sour cream – I want enjoyment.