Terms of Use. Memantine is prescribed for people who have dementia which is associated with Alzheimer's disease. List Memantine HCL side effects by likelihood and severity. This document does not contain all possible drug interactions. example, carbonic anhydrase inhibitors such as. A very serious allergic reaction to this drug is rare. Memantine, also known under the drug name Namenda, is a powerful nootropic that was first created in 1968 and is used as a prescription drug in the U.S. and Europe for the treatment of moderate to severe Alzheimer’s disease (AD). Use memantine with caution in patients with conditions that could affect urinary pH such as renal tubular acidosis (RTA), severe urinary tract infection (UTI), and renal failure. Rinse the syringe with water after each use. Are you planning to see a doctor about switching your medication? Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. It may help with delusions, aggression and agitation. The Global Deterioration Scale or GDS identifies seven stages of Alzheimer's disease that include stage 1 (no impairment), stage 2 (very It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions. Read the Patient Information Leaflet if available from your pharmacist before you start taking memantine and each time you get a refill. All rights reserved. Memantine (Namenda®) The first three are used to treat mild to moderate Alzheimer's. Patients with severe Alzheimer's may require 24-hour care and NAMENDA (memantine hydrochloride) is indicated for the treatment of moderate to severe dementia of the Alzheimer's type. Which drugs or supplements interact with memantine? Memantine may also be used for purposes not listed in this medication guide. The disease Alzheimer's is not curable but it can be managed by this specific drug. Medicines that make the urine more alkaline (for memantine 5 mg-10 mg tablets in a dose pack, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Treating Opioid Use Disorder With Medications, Constipated? You can find out more about medicines like memantine in the separate leaflet called Medicines for Dementia. This drug may make you dizzy. This medication works by blocking the action of a certain natural substance in the brain (glutamate) that is believed to be linked to symptoms of Alzheimer's disease. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. However, memantine will not cure AD or prevent the loss of these abiliti… 2. Talk to your pharmacist for more details. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Consult your doctor before breast-feeding. It can be used alone or with other Alzheimer’s disease treatments. It helps reduce dementia symptoms, but it … Memantine is in a class of medications called NMDA receptor antagonists. It can slow progression of symptoms in Alzheimer’s disease, like disorientation. It is used to help the symptoms which affect thinking, such as memory loss and confusion. Before taking memantine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Namenda is used to treat moderate to severe dementia of the Alzheimer's type. It is at times also used to improve general pain or parkinson disease. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions. H Capsules should not be crushed or chewed. Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. When discussing with patients and relatives, memantine can be said to be usually well tolerated, and to offer modest benefits for patients with moderate – severe dementia. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. It is thought that by blocking the NMDA receptor and the effects of glutamate, memantine may protect nerve cells from excess stimulation by glutamate. What should I know regarding pregnancy, nursing and administering Memantine HCL to children or the elderly? Things to remember when you fill your prescription. Memantine (Namenda, Namenda XR) is a medication prescribed for treating patient's with Alzheimer's disease and dementia. Consult your doctor or pharmacist if you have any questions. Call your doctor for medical advice about side effects. Other conditions and medication reactions can also cause dementia. This medication comes in tablet and oral (by mouth) solution forms and is usually taken once or twice daily, with or without food. Memantine is an amantadine derivative which is used for mild to severe Alzheimer's disease. Learn what Medicade and Medicare will provide for a patient. Do not double the dose to catch up. Do not mix it with water or other liquids. Memantine blocks this receptor and thereby decreases the effects of glutamate. Read More These drugs not only improve or stabilize mental functions, but they may also have positive effects on behavior and activities of daily living.They are not a cure for dementia, … Sign Up for MedicineNet Newsletters! These drugs - galantamine ( Razadyne - formerly known as Reminyl), donezepil ( Aricept ), rivastigmine ( Exelon ), and tacrine (Cognex) - … mg daily. three levels of severity: mild in which patients are alert and sociable, but Known by the trade name Namenda, it has been shown to be moderately effective for preventing the progression of the symptoms of some types of dementia. Discuss the risks and benefits with your doctor. Learn about dementia disorders such as Lewy Body Dementia, Alzheimer's disease (AD), Vascular (multi-infarct)... Use this guide for advice on caring for someone with Alzheimer's. I also agree to receive emails from MedicineNet and I understand that I may opt out of MedicineNet subscriptions at any time. Memantine is used for the treatment of moderate to You may need to start at a lower dose again and slowly increase it. The most common side effects of memantine are: Memantine may cause a serious skin reaction called Stevens-Johnson syndrome. Follow your doctor's instructions carefully. What does the science have to say about how it works and what it does? Treatment may involve psychotherapy and medication. Memantine is a prescription drug used to treat moderate to severe confusion (dementia) related to Alzheimer's disease. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not use a household spoon because you may not get the correct dose. It is less preferred than acetylcholinesterase inhibitors such as donepezil. However, the … What is Memantine (Namenda)? Memantine (Namenda) and a combination of memantine and donepezil (Namzaric®) are approved by the FDA for treatment of moderate to severe Alzheimer’s. example, It is not known if memantine is excreted into. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. How long have you been taking Memantine HCL? Memantine is an oral medication for treating patients with Alzheimer's disease. Alzheimer's disease can be not only mentally devastating to an indivdiual and family, it can also be emotionally devastating. Memantine is a prescription medication used to treat Alzheimer's disease. Generic Drugs, Are They as Good as Brand-Names? This is not a complete list of possible side effects. language skills. The drug, under various brand names, is also approved for use in Europe, China and elsewhere, and is available in various forms: as immediate-release tablets, as a solution, and as an extended-release medication.Clinical trial outcomes were assessed using three tests. The signs and symptoms of Alzheimer's disease depend on the stage of the disease. To help you remember, take it at the same time(s) each day. Memantine, commonly prescribed in the United States under the brand name Namenda, is for people with moderate-to-severe Alzheimer’s disease and vascular dementia. Some doctors and researchers disagree in regard to the number of stages of Alzheimer's disease (from You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. 12 Medicines That Could Help, moderate to severe Alzheimer's type dementia. Memantine, a drug approved by the FDA for the treatment of moderate to severe Alzheimer's disease that acts at the N-methyl-d-aspartate receptor, has been used off-label for various psychiatric disorders. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Namenda (memantine) reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. Capsules may be swallowed whole or opened and sprinkled on spoonsful Dementia is defined as a significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. Medically reviewed by John P. Cunha, DO, FACOEP; Board Certified Emergency Medicine. Memantine dosage. In Canada - Call your doctor for medical advice about side effects. USES: Memantine is used to treat moderate to severe confusion related to Alzheimer's disease. In 2003, the FDA approved Memantine for the treatment of both severe and moderate Alzheimer’s disease. Memantine uses. Memantine is intended to prevent an excess of glutamate from damaging the brain. Memantine uses, as this eMedTV page explains, are primarily concerned with treating moderate to severe dementia in people with Alzheimer's disease. Selected from data included with permission and copyrighted by First Databank, Inc. Is memantine safe to take if I'm pregnant or breastfeeding? Other medications used for Alzheimer's disease affect acetylcholine, one of the neurotransmitter chemicals that nerve cells in the brain use to communicate with one another. home/alzheimer's health center/alzheimer's a-z list/memantine article. Memantine is used to treat moderate to severe confusion (dementia) related to Alzheimer's disease. Memantine is used to treat moderate to severe Alzheimer's disease. Drug interactions may change how your medications work or increase your risk for serious side effects. severe dementia associated with Alzheimer's. Most people need to wait at least one week between dose changes. can no longer complete basic self-care tasks including washing, eating, and If your dose is different, do not change it unless your doctor tells you to do so. Store at room temperature away from light and moisture. It was first developed in the 1960s for the treatment of diabetes. Stress reduction, exercise, and medication are the standard treatments for fibromyalgia. 21 and 28 mg. Memantine may improve the ability to think and remember or may slow the loss of these abilities in people who have AD. Preparing financially for someone with Alzheimer's disease is an important task to complete so that bills get paid and the best coverage is provided. Alcohol or marijuana (cannabis) can make you more dizzy. If you notice other effects not listed above, contact your doctor or pharmacist. What conditions does Memantine HCL treat? Talk to your doctor if you are using marijuana (cannabis). Learn the early warning signs and symptoms of Alzheimer's disease. During pregnancy, this medication should be used only when clearly needed. 1 to 7 stages). Memantine is used to treat moderate to severe Alzheimer’s disease and dementia. Two key clinical studies carried out in the U.S. demonstrated that Namenda could ease Alzheimer’s symptoms patients, and led to approval by the U.S. Food and Drug Administration (FDA) in 2003. The amount of medicine that you take depends on the strength of the medicine. Namenda may also be used for purposes not listed in this medication guide.